MUSCLE MRI sequence study

• Research type

  Research Study

• Full title

  Novel Magnetic Resonance Imaging and UltraSound CLinical Evaluation of muscle pathology (MUSCLE study).

• IRAS ID

  161834

• Contact name

  Ai Lyn Tan

• Contact email

  a.l.tan@leeds.ac.uk

• Sponsor organisation

  The University of Leeds

• Duration of Study in the UK

  3 years, 0 months, 1 days

• Research summary

  The aim of this study is to assess a range of quantitative MRI and ultrasound measurement techniques for the assessment of muscle pathology. The feasibility and range of variation will be determined for each technique in each diagnostic group. In addition, the reproducibility of shearwave elastography, and its sensitivity and specificity for diagnosis will be calculated.

  This data will provide useful information about the best MRI and ultrasound techniques for diagnosis and suitable threshold values. The data will also inform the choice of techniques and power calculations for future longitudinal studies and studies of the effects of treatment.

• REC name

  London - Harrow Research Ethics Committee

• REC reference

  14/LO/1785

• Date of REC Opinion

  1 Oct 2014

• REC opinion

  Further Information Favourable Opinion