Multidisciplinary fatigue management programme for people with CMT

• Research type

  Research Study

• Full title

  A feasibility study of a multidisciplinary fatigue management programme, using acceptance and commitment therapy principles, for people with Charcot Marie Tooth disease (CMT).

• IRAS ID

  139872

• Contact name

  Margaret Phillips

• Contact email

  margaret.phillips@nottingham.ac.uk

• Research summary

  Fatigue is known to be a problem in Charcot Marie Tooth disease (CMT) and in other neuromuscular conditions. It impacts on several areas of daily life, such as employment and can affect quality of life. This study aims to use a multidisciplinary group intervention to reduce the impact of fatigue. Such interventions have been successful in other conditions such as traumatic brain injury and multiple sclerosisis. An important part of any intervention that may involve lifestyle and behavioural change is to use a consistent psychological approach, and we have chosen to use acceptance and commitment therapy. In this study we will test the feasibility of such an intervention for people with CMT, chosen as an example of a relatively common neuromuscular condition where fatigue is known to be a problem. The feasibility study will give us information on the acceptability and logistics of researching this intervention, which would then be used to inform a future clinical trial.
  Participants will be adults with CMT with a fatigue severity score of four or more recruited from the neuromuscular clinic at Royal Derby Hospital and will attend a seven week programme concerning different aspects of fatigue management. Each session will last two hours, with a break halfway through, in a group of 8-10 people, and will take place in a community setting. There will be an assessment visit beforehand where eligibility and initial measurements will be made, with further measures being taken in the last week of the intervention period and three months following the end of the intervention. It is funded from a fund held at Royal Derby Hospital derived from payments for a previous commercial study, and a small amount from a personal grant to Caroline Gray, co-investigator, from the Elizabeth Casson Trust.

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  14/EM/0044

• Date of REC Opinion

  14 Mar 2014

• REC opinion

  Further Information Favourable Opinion