MS200588-0004, Safety & Efficacy of MSB11022 in Rheumatoid Arthritis

  • Research type

    Research Study

  • Full title

    A multicenter, randomized, double-blind, phase III trial to evaluate the safety, immunogenicity, and efficacy of MSB11022 compared with Humira® in patients with moderately to severely active rheumatoid arthritis

  • IRAS ID

    215022

  • Contact name

    Christopher Edwards

  • Contact email

    cedwards@soton.ac.uk

  • Sponsor organisation

    Merck KGaA

  • Eudract number

    2016-002852-26

  • Duration of Study in the UK

    1 years, 7 months, 6 days

  • Research summary

    This is a phase 3 multicentre, double blind study of an investigational drug called MSB11022.

    The purpose of the study is to find out if MSB11022, the study drug, is as safe and effective as Humira®, an existing medication, for the treatment of moderate to severe Rheumatoid Arthritis (RA).

    Aproximately 260 people will participate in this study. The study will be conducted in approximately 60 medical centres in eight countries. The study will last until 2018.

    The study is made up of a screening period lasting up to 4 weeks, a treatment period of up to 52 weeks and a follow-up period lasting up to 16 weeks after the last dose of study medication.

  • REC name

    South Central - Hampshire A Research Ethics Committee

  • REC reference

    16/SC/0548

  • Date of REC Opinion

    5 Jan 2017

  • REC opinion

    Further Information Favourable Opinion