MS-PROACTIVE

  • Research type

    Research Study

  • Full title

    Preventing job loss using Acceptance and Commitment Therapy in Vocational Rehabilitation

  • IRAS ID

    279736

  • Contact name

    Helen L. Ford

  • Contact email

    helen.ford17@nhs.net

  • Sponsor organisation

    Leeds Teaching Hospitals NHS Trust

  • Clinicaltrials.gov Identifier

    NCT04515355

  • Duration of Study in the UK

    1 years, 11 months, 30 days

  • Research summary

    About 60-70% of people with multiple sclerosis (PwMS) lose employment within 10 years of the diagnosis. This can be due to complex personal and work-based factors including psychological factors. MS-PROACTIVE aims to test an online self-help therapy to support PwMS to stay in work called ‘READY for MS’. This is a type of Acceptance and Commitment therapy. It is a way to provide treatment in a flexible way without people having to go to see a psychologist.
    The aim of the treatment is to improve self-efficacy which has been shown to be a significant factor for helping PwMS who want to work to stay in work.
    The research team will initially develop an online version of READY for MS. We will ask 4 PwMS to test the online‘READY for MS’ and provide feedback and advice on any necessary changes. We will then recruit and randomise 88 PwMS in Leeds and London who are at risk of job loss. Participants in the active treatment group will use the online treatment in addition to their usual care; the control group will receive their usual care. The participants will complete questionnaires at the start of the study, at 8 weeks and 6 months measuring time off work and work instability (to measure risk of job loss), self-efficacy, mood, quality of life, fatigue and the impact of MS. The questionnaire data will be analysed to test the effectiveness of the treatment. The research team will also interview 4 PwMS at each site at the start of the study, at 8 weeks and 6 months to find out about their experience of using READY for MS in more detail. This will help to inform the use of READY for MS in a larger trial in the future.

  • REC name

    Yorkshire & The Humber - South Yorkshire Research Ethics Committee

  • REC reference

    20/YH/0199

  • Date of REC Opinion

    13 Aug 2020

  • REC opinion

    Further Information Favourable Opinion