MRI/CT augmented Guidance for Congenital Cardiovascular Interventions
Research type
Research Study
Full title
CT / MRI augmented guidance for X-ray fluoroscopic Congenital Cardiovascular Interventions
IRAS ID
194377
Contact name
Reza Razavi
Contact email
Clinicaltrials.gov Identifier
16/LO/2107, REC reference; 194377, IRAS project ID
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Background: Patients with congenital heart disease can have many catheter interventional procedures throughout their childhood to correct or improve structural problems associated with their heart condition. Their procedures are done under X-ray guidance and this can lead to a significant accumulation of X-ray dose they receive. We know that too many X-rays can cause many cancers and children are more susceptible than adults to their effects.
The idea: MRI scans do not involve any exposure to radiation and can produce highly detailed 3D pictures of the heart. Many of these patients also have MRI scans to clarify the anatomy and function of the heart before their catheter intervention procedure. Some patients have CT scans. Both CT/MRI images can be combined with X-ray pictures during the procedure using the latest techniques in image fusion technology.
What we want to do: We aim to implement this technology and assess its benefits in these patients of congenital heart disease, specifically by looking at which aspects of the procedure are improved with its use.
This is a single centre (GSTT NHS Trust Hospitals), device trial, which is prospective, largely qualitative and observational, lasting two years.
REC name
London - Westminster Research Ethics Committee
REC reference
16/LO/2107
Date of REC Opinion
6 Mar 2017
REC opinion
Further Information Favourable Opinion