MRI to guide treatment of abnormal heart rhythms

• Research type

  Research Study

• Full title

  Magnetic resonance imaging (MRI) to guide treatment of abnormal heart rhythms

• IRAS ID

  217417

• Contact name

  Mark O'Neill

• Contact email

  mark.oneill@kcl.ac.uk

• Duration of Study in the UK

  9 years, 11 months, 30 days

• Research summary

  Abnormal heart rhythms are common, affecting 1 in 20 people and can be difficult to treat. One of the main treatments is called ablation, which involves selectively destroying heart tissue causing the electrical ‘short circuits’ using specialised wires placed inside the heart. However, it can be difficult to identify the culprit heart tissue and to destroy it without damaging surrounding tissues.
  Magnetic resonance imaging (MRI) is a sophisticated imaging technique that is capable of identifying culprit heart tissue and visualizing ablation scar. MRI uses magnetic fields and radio-frequency waves, without exposure to radiation (X-rays).
  This study aims to use state-of-the-art MRI and ablation facilities to image the heart before and after ablation in order to improve the imaging techniques and to understand the contribution that they can make to improve outcome for ablation procedures.
  Number of participants – up to 500 patients undergoing a catheter ablation
  Number of sites – 1 (Guy’s and St Thomas’ Hospital NHS Foundation Trust)
  Sponsor – King’s College London; Co-sponsor – Guy’s and St Thomas’ NHS Foundation Trust
  Funding – Wellcome Trust Health Innovation Challenge Fund

• REC name

  London - Westminster Research Ethics Committee

• REC reference

  17/LO/0150

• Date of REC Opinion

  21 Mar 2017

• REC opinion

  Further Information Favourable Opinion