MRE in Chronic Liver Disease

• Research type

  Research Study

• Full title

  Assessment of Chronic Liver Disease Using Magnetic Resonance Elastography (MRE) (ACLAIM)

• IRAS ID

  260109

• Contact name

  Guruprasad Aithal

• Contact email

  Guru.Aithal@nottingham.ac.uk

• Sponsor organisation

  University of Nottingham

• Duration of Study in the UK

  7 years, 0 months, 0 days

• Research summary

  In chronic liver disease, scar tissue replaces normal liver tissue. We currently measure the degree of scarring in the liver by doing a liver biopsy. This involves taking a small sample of liver tissue to be assessed under a microscope. This procedure is invasive, and involves a small but significant risk.
  in Nottingham, we have developed new MRI techniques that can measure liver scarring and inflammation non-invasively. In this project, we would like to study new MRI technique called MR Elastograpy. This involves giving the liver external vibration and measuring the stiffness of the liver. We believe this technique can improve the diagnosis of liver scarring and inflammation.

• REC name

  East Midlands - Nottingham 2 Research Ethics Committee

• REC reference

  19/EM/0116

• Date of REC Opinion

  1 Aug 2019

• REC opinion

  Further Information Favourable Opinion