MQUEST
Research type
Research Study
Full title
Measuring subjective quality of vision and metamorphopsia before and after epiretinal membrane and macular hole surgery
IRAS ID
263121
Contact name
Chris Williams
Contact email
Sponsor organisation
Cardiff and Vale University Healthboard
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Metamorphopsia is a visual disorder in which straight lines appear distorted, it a common disorder in retinal conditions (conditions at the back of the eye) such as epiretinal membrane (ERM) and macular holes. A vitrectomy is the only treatment option for these conditions which involves surgery, removing the vitreous (jelly like substance) from the eye. As surgery is the only treatment option it would benefit the surgeon to gain a better understanding of the severity of metamorphopsia and how this affects quality of vision.
In clinical practice metamorphopsia is detected using an Amsler chart (a grid with lines) the patient is asked to look and the chart and draw where they can see distortion. This tool is not able to show the severity of metamorphopsia or how this affects quality of vision.
Recent clinical trials have shown the use of subjective questionnaires in analysing quality of vision and subjective metamorphopsia. The aim of the research is to compare two questionnaires to analyse subjective metamorphopsia and quality of vision in patients undergoing ERM and macular hole surgery.
We aim for patients to complete both questionnaires before and after having surgery to establish if there are any changes to the patients responses in relation to subjective quality of vision and metamorphopsia We will also compare the responses to other routine clinical tests to see if changes have occurred that correspond with the questionnaire responses.
Our aim is to identify if subjective questionnaires are a useful tool to analyse quality of vision and metamorphopsia in patients with ERM and macular holes. If questionnaires can be shown to be useful in assessing the severity of subjective metamorphopsia and how this affects quality of vision we would discuss if this could be used in a clinical setting to help with patient selection for surgery.REC name
South West - Cornwall & Plymouth Research Ethics Committee
REC reference
19/SW/0162
Date of REC Opinion
19 Sep 2019
REC opinion
Further Information Favourable Opinion