Mortality in MitraClip treated patients compared with standard care

• Research type

  Research Study

• Full title

  Mortality and healthcare resource utilization (HCRU) in patients treated with MitraClip compared with those treated with standard medical therapy for moderate or severe mitral regurgitation: a retrospective non-interventional study (NIS) in England

• IRAS ID

  251019

• Contact name

  Robert Smith

• Contact email

  R.Smith@rbht.nhs.uk

• Sponsor organisation

  Royal Brompton & Harefield NHS Foundation Trust

• Duration of Study in the UK

  0 years, 3 months, 0 days

• Research summary

  A retrospective NIS based on the secondary use of patient-level data obtained from the Hospital Episode Statistics (HES) database in order to describe all-cause mortality and healthcare resource utilization in patients treated with MitraClip compared with patients treated with standard medical therapy.

  Patients previously considered for MitraClip at the Royal Brompton and Harefield NHS Trust during 2015 to 2017 will be anonymously and securely identified in the HES database by NHS digital using information previously collected via the Commissioning through Evaluation programme.

• REC name

  East Midlands - Leicester Central Research Ethics Committee

• REC reference

  18/EM/0279

• Date of REC Opinion

  15 Oct 2018

• REC opinion

  Further Information Favourable Opinion