Modifiable risk factors for postoperative delirium in older adults.
Research type
Research Study
Full title
Modifiable risk factors for postoperative delirium in older adults; the PODIUM 1 study.(Post-Operative Delirium Investigation in the United kingdoM)
IRAS ID
204648
Contact name
Iain J McCullagh
Contact email
Sponsor organisation
Newcastle upon Tyne NHS foundation trust
Duration of Study in the UK
0 years, 4 months, 1 days
Research summary
We aim to conduct a prospective, cohort, feasibility study across the following five sites, Freeman Hospital and Royal Victoria infirmary ( The Newcastle Upon Tyne NHS Foundation Trust), James Cook University Hospital ( South Tees NHS Foundation Trust), Sunderland Royal Hospital ( City Hospitals Sunderland NHS Foundation Trust) and Wansbeck Hospital ( Northumbria Healthcare NHS Foundation Trust).
This feasibility study will aim to recruit 96 patients aged 65 years and older who are scheduled to undergo major elective surgery. Pre-operatively they will be assessed for delirium and undergo a series of questionnaires. Presence of postoperative delirium (POD) will be assessed on he first four postoperative days. We will record pre-existing health data, choice and dose of anaesthetic agents, use of depth of anaesthesia monitoring, regional versus general anaesthesia and post-operative analgesia as well as incidence of POD and overall severity of other post op complications. During this study (PODIUM 1) we will assess how easy ( or not) it is to recruit patients, how long it takes to gain consent and collect study data, and what proportion of each of these activities can be done by a regional trainee research network involved in this research project. We will use this information to construct a definitive, large scale cohort study to determine the modifiable risk-factors for postoperative delirium (PODIUM 2) in the UK. The overall aim of our research is to develop a peri-operative care bundle to decrease the incidence and severity of postoperative delirium which could be tested in a randomised control trial.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
17/NE/0183
Date of REC Opinion
27 Jul 2017
REC opinion
Further Information Favourable Opinion