Mobilising lower limb fluid for hemodynamic stability in haemodialysis
Research type
Research Study
Full title
Pilot evaluation of intermittent pneumatic compression and neuromuscular electrical stimulation for enhancing vascular refilling in haemodialysis
IRAS ID
137035
Contact name
David Keane
Contact email
Sponsor organisation
Leeds Teaching Hospitals NHS Trust
Research summary
Cardiovascular disease is the leading cause of death of dialysis patients and poor fluid management is associated with the increased risk. One of the principal limitations in avoiding chronic fluid overload in this patient group is the refilling rate - the rate at which fluid is transferred from tissues into the vascular system. If this rate cannot match the prescribed rate of fluid removal during dialysis the patient will end up with chronic fluid overload.
Two proposed methods of increasing the rate of refilling are intermittent pneumatic compression (IPC) devices, which increase the pressure of the fluid in tissue, and neuromuscular electrical stimulation (NMES) which activates the muscle pump and lymphatic drainage.
This investigation will trial the use of these two methods in patients suspected of having inadequate refilling rates. Outcome measures will be based on fluid status, presence of oedema and quality of life.
REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
14/YH/1091
Date of REC Opinion
30 Sep 2014
REC opinion
Further Information Favourable Opinion