MOA study
Research type
Research Study
Full title
A Mechanism of Action (MOA) study to characterise the effect of varying frequency of Spinal Cord Stimulation (SCS) on dorsal column fibre recruitment
IRAS ID
232165
Contact name
Stefano Palmisani
Contact email
Sponsor organisation
Saluda Medical Europe Ltd
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
0 years, 6 months, 30 days
Research summary
Electrical stimulation of the nerves in the spinal cord is a standard treatment for chronic pain. This treatment is commonly known as spinal cord stimulation (SCS), a treatment for which the patients have already been selected. In this study we want to examine the electrical signals in the nerves and how these signals change under varying frequencies.
The study will start after the patient signed the informed consent form and will take place during the first stage (test stage) of the SCS treatment. Participation in the study will last for up to 2 weeks and requires no extra visits to hospital. During the study we will connect the externalized wires to a recording device that will take measurements from the spinal cord at varying frequencies at 2 occasions. The frequencies that we will use are within the boundaries as normally used in the treatment of chronic pain.
REC name
London - Queen Square Research Ethics Committee
REC reference
18/LO/0344
Date of REC Opinion
21 Mar 2018
REC opinion
Favourable Opinion