Mitra v fingerprick tacrolimus creatinine

  • Research type

    Research Study

  • Full title

    Comparison of standard venous sampling for measurement of tacrolimus and creatinine versus fingerprick Mitra® volumetric absorptive microsampling in adult renal transplant recipients

  • IRAS ID

    245450

  • Contact name

    Jon Jin Kim

  • Contact email

    jonjin.kim@nuh.nhs.uk

  • Sponsor organisation

    Nottingham University Hospital

  • Duration of Study in the UK

    0 years, 3 months, 0 days

  • Research summary

    Patients with kidney transplant have blood tests very often. This is normally done in hospital and using a needle inserted into the vein. Two tests are important for kidney transplant patients - creatinine to monitor the health of the kidney; and tacrolimus to measure the level of the medicine which prevents rejection.

    This project wants to compare a fingerprick microsampling method to the standard venous blood. The fingerprick test is the same done by patients with diabetes and we use a microsampling tip which looks like a cotton bud to draw up a small amount of blood. Each tip draws up exactly 10 microlitres which is two drops. We require four microsampling tips. We want to compare the results of creatinine and tacrolimus done through the two methods.

    In the future, this would allow patients to do their creatinine and tacrolimus test at home. The tips dry completely and can be posted to the laboratory. We hope this will make life easier for transplant patients and also help them engage more with the care of their condition.

  • REC name

    West Midlands - South Birmingham Research Ethics Committee

  • REC reference

    18/WM/0176

  • Date of REC Opinion

    21 Jun 2018

  • REC opinion

    Favourable Opinion