Mitochondrial Research Biobank [MitoBank], Version 3

• Research type

  Research Tissue Bank

• IRAS ID

  342048

• Research summary

  Mitochondrial Research Biobank [MitoBank], Version 3

• REC name

  London - Bloomsbury Research Ethics Committee

• REC reference

  24/LO/0283

• Date of REC Opinion

  2 Aug 2024

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Cultured skin fibroblasts will be stored in cryotubes in secure liquid nitrogen storage and plasma samples a -80C, identifiable through a unique code.
  Personal data will be stored only in a GOSH password protected computer.
  Consent will be sought by the PI of the study (or a member of their clinical team) during regular clinic appointments.
  Collection of samples will be performed by trained healthcare professionals after consent for the procedure has been obtained, as per GOSH policy.

• Research programme

  The MitoBank will benefit patients with suspected or diagnosed mitochondrial disease. As mitochondrial diseases are rare conditions, the biobank will support deeper understanding of these conditions, expanding the knowledge of this group of rare disorders. This will give a valuable contribution to understanding disease mechanisms and pathophysiology and to development of new treatments. This will benefit patients, their relatives and carers, the medical teams managing their care, and the wider medical and scientific community interested in mitochondrial biology and disease.

• Storage license

  12220

• RTBTitle

  Mitochondrial Research Biobank [MitoBank], Version 3

• Establishment organisation

  UCL Great Ormond Street Institute of Child Health

• Establishment organisation address

  30 Guilford Street

  London

  WC1N 1EH