'Minimizing the pain of local anaesthesia'
Research type
Research Study
Full title
'Minimizing the pain of local anaesthesia. Use of pretreatment with dilute versus full strength local anaesthetic prior to the injection of the full strength local anaesthetic, double blinded randomized controlled trial'
IRAS ID
219995
Contact name
Saj Ataullah
Contact email
Sponsor organisation
Manchester University NHS Foundation Trust
Duration of Study in the UK
0 years, 2 months, 3 days
Research summary
Injection of the local anaesthetic into densely innervated periocular area can be very painful. We conducted a search on published techniques used to reduce the pain experienced during the injection and concluded that the method that we commonly use to minimize pain and enhance patient experience at the Manchester Royal Eye Hospital has not been well described in the world literature.
By performing prospective, randomized, controlled double blinded study we would like to prove that injection of 0.5 ml of diluted local anaesthetic (2% Lignocaine 1:5 with 0.9% NaCl) two minutes prior to injection of the full strength local anaesthetic (2% Lignocaine with 1:80000 Adrenaline 50:50 with 0.5% Bupivocaine with 1:200000 Adrenaline) significantly reduces pain experienced during administration of the local anaesthesia. The control arm: pretreatment with 0.5 ml of full strength local anaesthetic (concentration as described above) with further injection of full strength local anaesthetic two minutes later. Before the surgery is started, the injecting practitioner will fill in a pain score questionnaire with the patient to measure the level of discomfort experienced.REC name
North West - Liverpool Central Research Ethics Committee
REC reference
17/NW/0378
Date of REC Opinion
30 Jun 2017
REC opinion
Unfavourable Opinion