MIlkMAN: pilot study; version 1

• Research type

  Research Study

• Full title

  MIlk Intervention Muscle AgeiNg (MIlkMAN): pilot study

• IRAS ID

  241266

• Contact name

  Terry Aspray

• Contact email

  terry.aspray@newcastle.ac.uk

• Sponsor organisation

  North Tyneside General Hospital

• Clinicaltrials.gov Identifier

  N/A, N/A

• Duration of Study in the UK

  1 years, 2 months, 31 days

• Research summary

  Older adults experience a gradual decline in skeletal muscle mass, strength and function with ageing (sarcopenia), which puts them at increased risk of falls, frailty, disability, and death. Loss of muscle mass and strength can be
  accelerated further by other risk factors such as poor diet and physical inactivity. An adequate intake of dietary protein, including protein supplements and resistance exercise (RE) are recognised modifiable factors in muscle ageing and physical decline. However, while the importance of a ‘whole diet approach’ for health is well recognised, the role of whole foods (e.g. dairy, fish, and meats) in combination with RE for the prevention of sarcopenia in older adults is unclear. Whole milk is a source of high quality proteins, minerals, vitamins, and bioactive fats, and presence of these nutrients, especially protein:fat ratio, may be important for ageing muscle. The combination of whole milk and RE may help maintain muscle health without the need for drugs or dietary supplements.

  The main aim of the study is to examine the feasibility and acceptability of (whole) milk in combination with RE as an intervention to increase physical performance (PP), muscle strength, and mass in older adults aged 65 years and over at risk of sarcopenia. Asking: (1) Is an intervention of 2 × 500 ml milk (2 × 20 g of protein) after RE twice a week for 6 weeks feasible and (2) acceptable to community-dwelling older adults?

  This study will also explore the effect of RE combined with the consumption of whole milk versus skimmed milk versus fruit juice (supplemented with carbohydrates) on PP, muscle strength, mass, and self-reported quality of life, and activities of daily living in these participants.

• REC name

  North East - Newcastle & North Tyneside 1 Research Ethics Committee

• REC reference

  18/NE/0265

• Date of REC Opinion

  25 Sep 2018

• REC opinion

  Favourable Opinion