Microorganisms in the Human Respiratory Tract V1.0

• Research type

  Research Study

• Full title

  Understanding Factors that Regulate Respiratory Microbiota

• IRAS ID

  294539

• Contact name

  Laura Sadofsky

• Contact email

  l.r.sadofsky@hull.ac.uk

• Sponsor organisation

  University of Hull

• Duration of Study in the UK

  2 years, 11 months, 31 days

• Research summary

  The ultimate aim of the study is to identify factors that have the potential to mediate human respiratory microbiota. The research team aims to focus on patients with respiratory diseases and patients with gastro-intestinal (GI) conditions to understand microorganisms residing in the respiratory tract and the gut.
  Nasopharyngeal swabs and bronchoalveolar lavage (BAL) will be collected from patients undergoing bronchoscopy to represent URT and LRT respectively, for the investigation. Additionally, gastric specimens will be collected from patients undergoing gastroscopy, upper GI physiology testing, and patients with feeding tubes to understand whether the gut microbes are identical to the URT microbiota. Surplus samples will be used for the study except nasopharyngeal swabs collected from patients.

• REC name

  HSC REC A

• REC reference

  22/NI/0074

• Date of REC Opinion

  4 May 2022

• REC opinion

  Further Information Favourable Opinion