MICROFON STUDY
Research type
Research Study
Full title
Microcirculation and Vascular Function after Fontan Surgery - MICROFON STUDY
IRAS ID
297512
Contact name
Iain Squire
Contact email
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Fontan Surgery is done for children with only one working lower chamber of the heart called the 'Single Ventricle'. This surgery involves making connections between the two big veins that drain oxygen deficient blood to the heart and the lung artery directly. Fontan patients may develop long-term complications such as reduced heart function or oxygen levels, increased pressure in the veins, liver or kidney problems etc. The reasons for these complications are poorly understood. The small blood vessels in the body or ‘microcirculation’ are tiny (can be seen only by microscope) and they supply food and oxygen to the tissues. Very little is known about what happens to the microcirculation in adult Fontan survivors . In this study we want to understand why these adult Fontan survivors develop complications by looking at their microcirculation and comparing them with healthy people and those who were operated for other congenital heart diseases. The study will be conducted in East Midlands Congenital Heart Centre, Glenfield Hospital, Leicester. There is an option for home visit as well.
REC name
London - Bromley Research Ethics Committee
REC reference
22/LO/0851
Date of REC Opinion
16 Dec 2022
REC opinion
Further Information Favourable Opinion