Metabolomic profiling in renal cell carcinoma

  • Research type

    Research Study

  • Full title

    Observational prospective study to analyze a metabolomic profile and to explore it as prognostic factor in patients with renal cell carcinoma (mRCC)

  • IRAS ID

    136087

  • Contact name

    Tim Eisen

  • Contact email

    TGQE2@CAM.AC.UK

  • Sponsor organisation

    Cambridge University Hospitals NHS Foundation Trust and University of Cambridge

  • Research summary

    Research Summary
    The aim of the study is to study the levels of the metabolomic biomarkers in blood and urine. This might help us detect any variability of their levels in individual patients and between patients. This will help establish a range of these biomarkers in patients with kidney cancer.Patients will be requested to give us blood and urine samples on 2-3 occasions for this study, both of which will have to be at Addenbrooke’s Hospital. About 3-4 teaspoons of blood and an eggcup full of urine sample will be collected on each occasion.

    Summary of Results
    It proved disappointingly difficult to collect the necessary samples from this project. In order not to waste materials kindly supplied by study participants, approvals were obtained to transfer samples to larger Cambridge sample collections called ARTIST and DIAMOND.

  • REC name

    East Midlands - Leicester South Research Ethics Committee

  • REC reference

    13/EM/0475

  • Date of REC Opinion

    20 Dec 2013

  • REC opinion

    Favourable Opinion