Mental Health Mission Mood Disorder Cohort Study
Research type
Research Study
Full title
Mental Health Mission Mood Disorder Cohort Study
IRAS ID
345799
Contact name
Michael Browning
Contact email
Sponsor organisation
University of Oxford Research Governance, Ethics and Assurance
Duration of Study in the UK
2 years, 5 months, 31 days
Research summary
The Mental Health Mission Mood Disorder Cohort Study aims to improve the understanding and treatment of mood disorders including major depressive disorder (MDD) and bipolar disorder (BD). These conditions are significant contributors to global disability, and existing treatments aren’t effective for everyone. This study will follow individuals diagnosed with these disorders to gather extensive data over time, helping researchers to identify why some people respond better to treatments than others.
The study will recruit patients with MDD or BD from participating UK clinics in the Mental Health Mission Mood Disorder Network, involving approximately 2,000 participants, with a maximum of 5,000 participants. Participants will undergo clinical assessments, and their medical information, along with self-reported data on mental health, wellbeing, and quality of life will be securely stored. This data will be used to help develop more personalised approaches to treatment and identify factors influencing treatment outcomes.Participants can also provide biosamples (blood or saliva) and complete optional online cognitive tasks. They will be asked to complete questionnaires every three months, over a period of up to three years, with an option to stop at any time. Additionally, participants may agree to their data being linked to national databases (like NHS records) and could be contacted for future research studies).
This study is funded by the National Institute for Health and Care Research, and its primary objective is to establish a research-ready cohort that supports ongoing and future mental health research, benefiting both participants and the wider community.
REC name
London - Surrey Borders Research Ethics Committee
REC reference
25/LO/0463
Date of REC Opinion
23 Jul 2025
REC opinion
Further Information Favourable Opinion