Meniscal Tear Outcome Cohort (MenTOC)

• Research type

  Research Study

• Full title

  Meniscal Tear Outcome Cohort (MenTOC)

• IRAS ID

  217769

• Contact name

  Simon Abram

• Sponsor organisation

  University of Oxford

• Duration of Study in the UK

  3 years, 9 months, 31 days

• Research summary

  This is a prospective cohort study of participants referred to hospital (secondary care) for assessment of their knee pain and undergoing MRI of the knee. Patients will be reviewed in clinic and, according to standard clinical practice, will be offered arthroscopic meniscectomy for unstable meniscal tears with associated symptoms that the patient feels are severe enough to consider this intervention. In other cases, such as patients with stable meniscal tears or underlying knee osteoarthritis, patients may be offered alternative treatment such as physiotherapy or management according to the knee osteoarthritis treatment pathway.

  The primary outcome of the study will be change in the patients' reported symptoms and limitations, assessed by completion of a range of PROMs (Patient Reported Outcome Measures: KOOS, Lysholm, WOMET, MSK-HQ). The majority of these PROMs have previously been validated in some groups of patients with meniscal tears but there is a need to evaluate their validity further in a sub-group of patients with unstable meniscal tears and without underlying osteoarthritis in the knee. Secondary outcomes include transition in patient symptoms, patient satisfaction, pain scores and other open questions.

  Patients will be invited to participate in the outcomes evaluation and also asked to indicate if they would be interested in attending focus groups or interviews for a qualitative sub-group study. The identification of those patients invited to attend interviews will be based upon the patient’s clinical record including the results of any standard care investigations and clinical findings. This qualitative sub-study will investigate how well patient symptoms are represented by the domains of the currently available PROMs and the general treatment expectations and concerns of patients.

• REC name

  London - Camden & Kings Cross Research Ethics Committee

• REC reference

  17/LO/0116

• Date of REC Opinion

  25 Jan 2017

• REC opinion

  Favourable Opinion