MENB REC 2ND GEN-096 BST:002,055,058

  • Research type

    Research Study

  • Full title

    A Phase 3b, open-label, multi-center study to assess the immune response and safety of the meningococcal group B vaccine rMenB+OMV NZ when administered to healthy participants aged 10 to 20 years old, who were primed during the first 2 years of life

  • IRAS ID

    1011963

  • Contact name

    Paolo Chiarini

  • Contact email

    paolo.x.chiarini@gsk.com

  • Sponsor organisation

    GSK Vaccines S.r.l.

  • Research summary

    The trial is a vaccine study that will have two treatment groups, Bexsero naive participants and those that receive Bexsero as children. Bexsero is approved in this indication in the UK, but as a one off treatment. This study is testing the advantage of using the medication as a booster. Therefore Naive patients will receive 2 vaccinations in this trial, 30days apart and the Bexsero experienced group will receive one vaccination, to boost their old vaccination. The age group is 10-20years. Every patient will have 2 visits in site to perform the vaccination, blood tests and examinations needed for this trial.

  • REC name

    London - Westminster Research Ethics Committee

  • REC reference

    25/LO/0228

  • Date of REC Opinion

    30 Apr 2025

  • REC opinion

    Further Information Favourable Opinion