MeIn/10/Ran-Cad/003

• Research type

  Research Study

• Full title

  EFFICACY OF RANOLAZINE IN PATIENTS WITH CORONARY ARTERY DISEASE (CAD)

• IRAS ID

  82626

• Contact name

  Chim Lang

• Contact email

  c.c.lang@dundee.ac.uk

• Sponsor organisation

  Menarini International Operations Luxembourg SA

• Eudract number

  2011-001278-24

• ISRCTN Number

  34

• Clinicaltrials.gov Identifier

  34

• Research summary

  The aim of the study is to demonstrate the effect of ranolazine, on top of standard therapy, in patients with Coronary Artery Disease (CAD) characterized by angina and limited exercise capacity on treadmill test.
  Overall the study will recruit 1216 randomised patients (608 treated with ranolazine and 608 treated with placebo) with CAD confirmed by angiography, prior Myocardial Infarction (MI) or prior revascularization (Percutaneous coronary intervention - PCI, Coronary artery bypass surgery - CABG) and with exercise induced angina not controlled by their standard therapy.

• REC name

  East of Scotland Research Ethics Service REC 2

• REC reference

  14/ES/1007

• Date of REC Opinion

  11 Nov 2011

• REC opinion

  Further Information Favourable Opinion