Measuring what matters in depression based on Deprivation Decile
Research type
Research Study
Full title
Exploring Quantitative Disparities in DAS and PHQ-9 Scale Scores through Index of Multiple Deprivation Decile: A Logistic Regression Analysis
IRAS ID
335499
Contact name
Gary Brown
Contact email
Sponsor organisation
The Royal Holloway, University of London
Clinicaltrials.gov Identifier
Not applicable , Not applicable
Duration of Study in the UK
0 years, 9 months, 3 days
Research summary
Depression is widely acknowledged as heterogeneous condition that require accurate and multidimensional assessment approach to facilitate personalised treatment plans (Maj et al. 2020; Reynolds, 2020; Lépine & Briley, 2011; Cuijpers, 2019). Although there are numerous self-rating depression screening tools, Patient Health Questionnaire-9 is the most widely used which is synonymous with symptom severity evaluation ((Miller et al., 2021; Manea et al., 2015; Kroenke, Spitzer & Williams, 2001; Kroenke et al., 2010). However, some of its shortcoming includes inability to capture lived experience and failure to report on what matters to the patients (Malpass at al., 2010; Robinson et al., 2017; Mitchell et al., 2011). Contrary to PHQ-9, Dysfunctional Attitude Scale focuses on contextual issues relating to core beliefs associated with depression. However, it is an exclusive expert-developed tool (Weissman, 1979).
Additionally, there are reported disparities in self-rated health measures across individuals from different socioeconomic statuses (SES) (Dowd & Zajacova, 2010; Taheri et al., 2019). For example, Ryu et al. (2018) found that low socioeconomic status based on individual’s housing characteristics was associated with inconsistent in self-reporting of health status. Hence, exploring how those from low and high SES differ in response to items of DAS and PHQ-9 is also a key issue yet to be addressed.The current study will analyse anonymised data from approximately 3500 patients who have received depression treatment through the Homerton University Hospital NHS Foundation Trust's Talk Changes - NHS IAPT service in City and Hackney. The primary objective is to investigate potential quantitative differences in the DAS and PHQ-9 scores based on patients' deprivation levels associated with their residential areas.
REC name
South Central - Hampshire B Research Ethics Committee
REC reference
24/SC/0061
Date of REC Opinion
15 Feb 2024
REC opinion
Further Information Favourable Opinion