Measuring hydrogen peroxide in exhaled breath condensate in HV
Assessment and validation of a device for measuring hydrogen peroxide in exhaled breath condensate in Healthy Volunteers
Imperial College London
Duration of Study in the UK
0 years, 11 months, 31 days
The purpose of this study is to evaluate the performance of an Exhaled Breath Condensate (EBC) device. EBC measurements can be used for the assessments of lung inflammation in asthma and chronic obstructive pulmonary disease (COPD). Current assessments are based on patient symptoms and simple spirometry tests. Unfortunately, these tests are not directly correlated to lung inflammation in these diseases.
Exhaled Breath Condensate (EBC) serves as a simple and non-invasive measurement which can potentially inform clinical decision-making. EBC measures hydrogen peroxide (H2O2) concentrations in exhaled breath and significantly higher concentrations are found in COPD patients. Following a successful pilot study we now want to evaluate the device with real breath samples from healthy volunteers. We want to evaluate the consistency of 3 measurements a month apart.
London - Surrey Research Ethics Committee
Date of REC Opinion
21 Apr 2021
Further Information Favourable Opinion