Measurement of preplatelets in inherited and acquired thrombocytopenia

  • Research type

    Research Study

  • Full title

    Measurement of preplatelets in inherited and acquired thrombocytopenia

  • IRAS ID

    188445

  • Contact name

    Paul Harrison

  • Contact email

    p.harrison.1@bham.ac.uk

  • Sponsor organisation

    University of Birmingham, Research Support Group

  • Clinicaltrials.gov Identifier

    N/A, N/A

  • Duration of Study in the UK

    0 years, 6 months, 6 days

  • Research summary

    Studying levels of young platelets has the potential to identify whether low platelet counts are a result of increased destruction or decreased production of platelets.
    The research to be undertaken will utilise a number of methods to study platelets in blood samples from consenting individuals.
    Recruited participants will be given separate information sheets and consent forms specific to the study group they fall under. The study groups include healthy volunteers and different causes of low platelet counts.
    Up to 10ml of whole blood will be taken by a heath care professional in addition to any blood collected for routine clinical tests.
    The samples will be anonymised immediately using a coding system and transported to the Centre for Translational Inflammation Research in the Queen Elizabeth Hospital, Birmingham.
    Blood samples will be studied using cell counters to quantify the populations of platelets and imaging techniques to visualise young platelets.
    The research will not affect the care received by the participants.

  • REC name

    West Midlands - South Birmingham Research Ethics Committee

  • REC reference

    15/WM/0465

  • Date of REC Opinion

    7 Jan 2016

  • REC opinion

    Further Information Favourable Opinion