MEASURE AAVitHS
Research type
Research Study
Full title
Multi-Country, Cross-Sectional Study to Characterize Real-World Burden of Disease in Adolescent and Adult Patients with Alopecia Areata, Vitiligo, or Hidradenitis Suppurativa (MEASURE AAVitHS)
IRAS ID
358544
Contact name
Kave Shams
Contact email
Sponsor organisation
AbbVie
Duration of Study in the UK
2 years, 0 months, 3 days
Research summary
This study is a cross-sectional, multi-country, observational study involving Adolescent and Adult Patients with Alopecia Areata (AA), Vitiligo, or Hidradenitis Suppurativa (HS) in real-world clinical practice. Both patient-reported and physician-reported outcomes will be documented.
Alopecia areata (AA) is a condition that causes patchy hair loss, typically on the scalp, but can also affect other areas such as the eyebrows, beard, or body hair. It’s an autoimmune condition where the immune system mistakenly attacks the hair follicles, leading to sudden hair loss.
Vitiligo is a chronic (long-lasting) autoimmune disorder that causes patches of skin to lose pigment or colour. This happens when melanocytes (skin cells that make pigment) are attacked and destroyed, causing the skin to turn a milky-white colour.
Hidradenitis suppurativa (HS) is a painful, long-term skin condition that causes skin abscesses and scarring on the skin. The exact cause of hidradenitis suppurativa is unknown, but it occurs near hair follicles where there are sweat glands, usually around the groin, bottom, breasts and armpits.
The study will consist of collecting primary data in a single visit where participants will complete the paper Patient Reported Outcome (PRO) questionnaires. In addition, physician reported outcomes will be documented by completion of the relevant Clinical questionnaires. Clinical data will also be collected from the patients medical records
There will be no changes to patient management for the study or additional visits. It will be conducted in 7 centres in the UK, who will enrol approximately 250 patients.REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
25/YH/0195
Date of REC Opinion
10 Nov 2025
REC opinion
Further Information Favourable Opinion