Maternal obesity and offspring mental health

  • Research type

    Research Study

  • Full title

    Maternal pre-pregnancy obesity and risk of mental health disorders in the offspring

  • IRAS ID

    212025

  • Contact name

    Rebecca Reynolds

  • Contact email

    r.reynolds@ed.ac.uk

  • Sponsor organisation

    University of Edinburgh

  • Duration of Study in the UK

    0 years, 11 months, 31 days

  • Research summary

    Mental health problems are common and place significant burden on the individual, their family and society. There is a need to understand the underlying causes. Evidence suggests that risk of mental health disorders may be determined during very early fetal development in the womb. Maternal health, and particularly maternal obesity is a potential factor contributing to risk of mental health problems in the offspring. This is very relevant as currently 1 in 5 women in the UK are obese at the time of pregnancy. A few studies have investigated this but the results have been inconsistent due to small study size and limited duration of follow up. We plan to use a unique database, The Aberdeen Maternity and Neonatal Databank to address this question as it contain data on mums and their babies since the 1950s to present day and also has information about maternal weight in pregnancy. If our findings enable us to identify risk factors for mental disorders, this might then in the future lead to the possibility of developing targeted preventive interventions for mental disorders.

  • REC name

    London - Dulwich Research Ethics Committee

  • REC reference

    16/LO/1410

  • Date of REC Opinion

    20 Jul 2016

  • REC opinion

    Favourable Opinion