MATCH LTFU
Research type
Research Study
Full title
MAcrophage Therapy for Liver Cirrhosis- Long Term Follow Up
IRAS ID
320456
Contact name
Stuart Forbes
Contact email
Sponsor organisation
University of Edinburgh
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
3 years, 0 months, 28 days
Research summary
The Macrophage study for liver cirrhosis (MATCH) randomised controlled trail (RCT) completed in August 2022. At the conclusion of the trial, it has become apparent that we understand the longer term outcomes of participants within the study cohort to determine longer-term safety and the durability of treatment responses.
The aim of the MATCH Long Term Follow up (LTFU) study is to continue to collect clinical data for the participants that took part in the MATCH RCT trial, this data will be collected remotely, with no study visits, and no additional interventions other than that directed by their usual liver doctors. Data recorded at the participant’s routine clinic visits will be collected remotely over a three year period, By doing so, comprehensive clinical outcome data, on a well characterised cohort of cirrhotic patients enrolled in an interventional study, will be obtained. This study is therefore an important milestone in the overall aim of the original MATCH study.REC name
West of Scotland REC 1
REC reference
22/WS/0175
Date of REC Opinion
14 Dec 2022
REC opinion
Favourable Opinion