MARI
Research type
Research Study
Full title
Multicentre study investigating the effects of aneurysm repair surgery on renal function and acute kidney injury (AKI)
IRAS ID
214819
Contact name
Ceri Jones
Contact email
Sponsor organisation
University Hospital Coventry and Warwickshire RD&I
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Abdominal aortic aneurysm (AAA) is a common cause of cardiovascular death in the UK. The only treatment for AAA is surgical repair, which can be done either with open surgery (OAR) or endovascular minimally invasive surgery, which is commonly referred to as EVAR. Both types of repair can impact on kidney function and cause acute kidney injury (AKI). Long-term (chronic) damage to the kidneys is also common after these types of surgery. However, the exact number of patients that develop AKI and chronic kidney disease after EVAR or OAR is not known and most importantly, the impact of these adverse events on death rates and morbidity after surgery is unclear. In this study we will collect data from 6 centres in the UK regarding the incidence of AKI after EVAR or OAR and assess their effect on overall kidney function as well as mortality/morbidity.
REC name
HSC REC B
REC reference
16/NI/0239
Date of REC Opinion
15 Nov 2016
REC opinion
Further Information Favourable Opinion