MAP-BRONJ
Research type
Research Study
Full title
The multidisciplinary approach to the prevention of Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ). A Qualitative study into the attitudes and perceptions of patients. (MAP-BRONJ)
IRAS ID
216783
Contact name
Andrew Sturrock
Contact email
Sponsor organisation
University of Sunderland
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
A group of drugs called bisphosphonates are used to treat a number of conditions that effect bones, such as osteoporosis and certain cancers. Because we are living longer, more patients are being prescribed these drugs than ever before and a rare but important side effect, called osteonecrosis of the jaw, has been discovered.
This side effect causes problems with patient’s jawbones, particularly if patients require a dental extraction. This unpleasant and painful condition which is characterised by exposure of necrotic bone, can be difficult to treat and usually requires surgery to cut away part of the jawbone. Due to the difficulty in treating this condition, healthcare professionals should try to prevent it from happening in the first place.
We should be discussing this risk with patients and advising that they get a dental check-up before and during bisphosphonate treatment. Current evidence suggests that this does not happen, patients are unaware of the problem and knowledge of this risk is poor among patients and healthcare professionals.
This study is designed to look at the attitudes of patients towards this risk, the ways in which we can minimise this risk and how professionals and patient can work better as a team to prevent it. To do this, the research team will carry out a number of in depth interviews with patients to explore their perspectives. The interviews will be anonymised, transcribed and analysed to identify themes.
The results of this project may help with the development of services that can reduce the risk of patients experiencing osteonecrosis of the jaw and to gain an understanding of the role of each healthcare professional in the management of this condition.
REC name
North East - York Research Ethics Committee
REC reference
17/NE/0033
Date of REC Opinion
22 Feb 2017
REC opinion
Further Information Favourable Opinion