Manchester Lung Health Study
Research type
Research Study
Full title
An observational cohort study investigating the impact of community-based lung cancer screening across a deprived geographical area and the role of biomarkers for the early detection of lung cancer.
IRAS ID
252263
Contact name
Phil Crosbie
Contact email
Sponsor organisation
Manchester University NHS Foundation Trust
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
The Manchester Lung Health Study (qUEST) will assess the uptake of a community-based lung cancer screening service and its impact across a deprived area of North and East Manchester, which has high rates of lung cancer. One measure will be to compare the number and stage of lung cancers detected through screening to those detected outside of screening. In addition we will investigate the potential of a blood and nose test to detect lung cancer or to help decide who would benefit from screening. We will also see if these samples can help with the interpretation of CT scans. One of the problems with lung cancer CT screening is that you detect lung nodules in which we are not sure if they are benign or cancerous. Therefore we are also looking to see if a biomarker can help us work out which are cancerous and which are benign.
REC name
London - Brent Research Ethics Committee
REC reference
19/LO/0404
Date of REC Opinion
9 May 2019
REC opinion
Further Information Favourable Opinion