Macular Hole Imaging by AO-SLO (version 1.0)
Research type
Research Study
Full title
Macular Hole Imaging by Adaptive Optics Scanning Laser Ophthalmoscopy
IRAS ID
173369
Contact name
James Bainbridge
Contact email
Sponsor organisation
Moorfields Eye Hospital NHS Foundation Trust
Duration of Study in the UK
1 years, months, days
Research summary
Macular hole is a blinding condition in which a hole develops in the central part of the retina, which is the layer of light-sensitive cells in the eye. The condition causes sight loss in approximately 2 in every 1000 individuals and can have a devastating impact on quality of life and independence. Surgery can close the hole in approximately 90% but the benefit to sight is unpredictable. Why is sight not fully restored? The answer is not known but may reflect damage to the light-sensitive photoreceptor cells called “cones”. We aim to find out if this is the case using a powerful new imaging technique which, for the first time, can identify individual cones. The results will enable us to inform people with more confidence what benefits they can expect from surgery.
REC name
London - Brighton & Sussex Research Ethics Committee
REC reference
15/LO/1696
Date of REC Opinion
19 Oct 2015
REC opinion
Further Information Favourable Opinion