MACE study
Research type
Research Study
Full title
THE ACCURACY AND ACCEPTABILITY OF MAGNET ASSISTED CAPSULE ENDOSCOPY IN THE DIAGNOSIS OF OESOPHAGEAL PATHOLOGY: AN OBSERVATIONAL STUDY\n
IRAS ID
186518
Contact name
K RAGUNATH
Contact email
Sponsor organisation
University of Nottingham
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
Oesophageal cancer tends to present once at an advanced stage and is associated with a 5 year survival rate of just 13%. There is therefore an emphasis on looking for precursor conditions such as Barrett’s oesophagus. This is often diagnosed when patients undergo a gastroscopy for other reasons. It is likely that there is a significant proportion of patients with undiagnosed Barrett’s oesophagus, who do not benefit from the established surveillance programme. \n\nIn this study, we plan to see whether magnet assisted capsule endoscopy (MACE) can accurately diagnosis Barrett’s oesophagus and therefore become a potential tool for screening. This has potential to be useful in the diagnosis and surveillance of oesophageal varices, and therefore will also be included in this study. This involves swallowing a pill sized capsule, within which is imaging technology. The MACE is magnetically steerable, allowing for views of the oesophagus in real time.\n\nPatients will be selected from a group of patients with known Barretts oesophagus, oesophageal varices and those undergoing an endosdcopy for alternate indications. The findings of MACE and the subsequent endoscopy will be compared.
REC name
East Midlands - Derby Research Ethics Committee
REC reference
16/EM/0089
Date of REC Opinion
20 Apr 2016
REC opinion
Further Information Favourable Opinion