Lung Cancer Detection using Blood Exosomes and HRCT

• Research type

  Research Study

• Full title

  Improving the early detection of lung cancer by combining exosomal analysis of hypoxia with standard of care imaging.

• IRAS ID

  261766

• Contact name

  Tony Ng

• Contact email

  tony.ng@kcl.ac.uk

• Sponsor organisation

  King's College London

• Duration of Study in the UK

  3 years, 11 months, 31 days

• Research summary

  This project aims to validate exosomal assays that are based on hypoxia detection as potential biomarkers of early detection.
  We will determine whether the assay can detect clinical lung cancer at the time of imaging and interval cancers during subsequent follow up. We will also establish preliminary sensitivity/specificity data for the "combined CT/exosomal risk stratification marker" and provide initial data on the potential association of the "combined CT/exosomal risk score" with the subsequent cancer progression and treatment response.

• REC name

  East of England - Cambridgeshire and Hertfordshire Research Ethics Committee

• REC reference

  19/EE/0357

• Date of REC Opinion

  20 Dec 2019

• REC opinion

  Further Information Favourable Opinion