Low-field MRI for Lung Diseases - LoMRLung Study
Research type
Research Study
Full title
Optimisation of Low-Field Magnetic Resonance Imaging for Thoracic Pathologies
IRAS ID
358263
Contact name
Carolyn Horst
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
CT (computed tomography) scans are currently the primary method used to image the lungs, because they produce clear images quickly. However, CT uses radiation, and alternatives like MRI (magnetic resonance imaging) have so far been limited to specific conditions, such as lung cancer, cystic fibrosis, and pulmonary hypertension.
Low-field MRI (LFMRI) is a newer approach that uses lower magnetic fields (around 0.55 Tesla). It has advantages for lung imaging, including reduced image artefacts, improved portability, and lower running costs. This technology opens up the possibility of offering high-quality lung imaging outside of large hospital centres, including community settings.
Recent research suggests that LFMRI could help in diagnosing and monitoring lung diseases, but more studies are needed. Scan times still need to be shortened, and new imaging sequences developed, to make the process quicker and more comfortable for patients.
The purpose of this proof-of-concept study is to optimise low-field MRI protocols for lung imaging and assess how well it detects lung disease compared to the current gold standard, CT scans. In addition to evaluating the image quality, we will gather feedback from participants about their experience of undergoing a LFMRI scan.
The study will also explore whether LFMRI can capture functional information about the lungs, such as ventilation patterns, and whether scan findings are linked to clinical measures like breathing test results or oxygen levels.
Through this research, we aim to support the development of safer, more accessible imaging options for people with lung conditions, while improving the experience of patients undergoing diagnostic scans.
REC name
London - West London & GTAC Research Ethics Committee
REC reference
25/LO/0878
Date of REC Opinion
6 Jan 2026
REC opinion
Further Information Favourable Opinion