Lothian NRS BioResource

• Research type

  Research Tissue Bank

• IRAS ID

  355661

• Research summary

  Lothian NRS BioResource

• REC name

  East of Scotland Research Ethics Service REC 1

• REC reference

  25/ES/0030

• Date of REC Opinion

  21 May 2025

• REC opinion

  Favourable Opinion

• Data collection arrangements

  Lothian NRS BioResource is based in NHS Lothian. The tissue bank supports a wide range of research involving disorders of the human body. The material collected is from living donors and consists of tissue surplus to diagnostic requirements, or that has been removed for therapeutic reasons and would normally be discarded.

  Tissue and tissue derivatives are stored either snap frozen or as paraffin embedded wax blocks. The collection of paraffin embedded tissue samples includes material in the pathology diagnostic archive. The diagnostic archive also includes surplus tissue and samples available from the other Laboratory Medicine labs including Haematology, Biochemistry, Microbiology and Virology.

  The type of de-identified data linked to the samples depends on the requirements of the research project but only the minimum required is provided. It typically includes demography, diagnosis and pathological findings. The data is derived from health records and is held on secure databases. Additional data can be provided via collaboration with the local Safe Haven if their requirements for governance are met.
  

• Research programme

  The aim of the Lothian NRS BioResource is to support research in accordance with the research strategies set out by the CSO and also those of local and UK-wide research groups. The Lothian BioRsource is also part of the NRS Biorepository network in Scotland. The Lothian NRS BioResource welcomes applications form all types of organisations including clinical, academic and commercial researchers. A wide range of disease and non-diseased tissue is available for research. The research interests supported are varied and include, but not limited to, studies on cancer, inflammatory disease, liver disease, metabolic disease, infectious disease, neurological conditions and reproductive conditions. The fields of research supported include translational research, genetics, genomics, proteomics, molecular pathology, biomedical sciences and cell culture

• Storage license

  N/A

• RTBTitle

  Lothian NRS BioResource

• Establishment organisation

  NHS Lothian

• Establishment organisation address

  Mainpoint

  102 Westport

  Edinburgh

  EH3 9DN