Longitudinal Study of Autonomic Function and Cancer
Research type
Research Study
Full title
Longitudinal Pilot Study of the Effect of Colorectal Cancer and its Treatment on Autonomic Tone
IRAS ID
192442
Contact name
Stephen Perring
Contact email
Sponsor organisation
Poole Hospital NHS Foundation Trust
Duration of Study in the UK
2 years, 0 months, 30 days
Research summary
We propose a pilot study to see whether the autonomic nervous system is compromised by cancer or its treatment. We suspect this because other research has indicated a high incidence of autonomic damage in patients with advanced cancer. Also symptoms of cancer and its treatment are very similar to those of patients with autonomic dysfunction. We also wish to see whether any autonomic damage observed is permanent or if it is recoverable if the patient is successfully treated and moves into remission. Patients with colorectal cancer will be assessed for autonomic tone following diagnosis but before treatment, on at least one occasion mid-treatment and following treatment if successful.
REC name
South West - Frenchay Research Ethics Committee
REC reference
16/SW/0094
Date of REC Opinion
25 Apr 2016
REC opinion
Unfavourable Opinion