Longitudinal EEG markers of neuropathic pain

• Research type

  Research Study

• Full title

  Longitudinal Analysis of EEG Markers of Central Neuropathic Pain in Spinal Cord Injury

• IRAS ID

  310267

• Contact name

  Aleksandra Vuckovic

• Contact email

  aleksandra.vuckovic@glasgow.ac.uk

• Sponsor organisation

  NHS Greater Glasgow and Clyde

• Duration of Study in the UK

  2 years, 5 months, 31 days

• Research summary

  In this study, we will be looking into brain waves related to Central Neuropathic Pain (CNP) following Spinal Cord Injury (SCI). All participants will be life-long patients of the Queen Elizabeth National Spinal Injuries Unit (QENSIU).
  We want to establish a relationship between one’s personal pain rating and their brain waves recorded by electroencephalography (EEG).
  We will recruit 10 adults with chronic SCI and CNP to provide them with a wearable EEG device and a computer tablet with games that test cognitive ability. The Cumulus Neuro from Northern Ireland provides this equipment.
  We shall teach participants to use EEG and tablet either face to face or over the Internet. After that, we’ll ask them to use it independently (or with carers) at home. They will record their EEG while playing games on 10 days over a period of two months. Every day when they use the system, they will use it twice, first time before taking pain medication and second time two hours later, after taking pain medications. One session will last 45-60 min, including comfort breaks. After recording EEG, they will send coded data (all participants will have their ID number instead of name) over the Internet to the safe cloud space maintained by company Cumulus Neuroscience. The Company will inspect quality of EEG recording, remove noise and send data over safe file exchange transfer to researcher at the University of Glasgow. The researchers will perform further data analysis. Participants in the study will return EEG and tablet to Cumulus Neuroscience at the end of the study.
  

• REC name

  London - Hampstead Research Ethics Committee

• REC reference

  22/PR/1090

• Date of REC Opinion

  25 Oct 2022

• REC opinion

  Further Information Favourable Opinion