Long-term health outcomes following childhood hospital admissions
Research type
Research Study
Full title
Long-term health outcomes following childhood hospital admissions
IRAS ID
251738
Contact name
Pia Hardelid
Contact email
Sponsor organisation
UCL Great Ormond Street Institute of Child Health
Clinicaltrials.gov Identifier
1617-0224, Public Benefit and Privacy Panel (PBPP - Scotland); 18PE17, R&D number - subproject 2 (PhD studentship); 1398461, R&D number - subproject 1 (Rutherford fellowship); 1516-0405, Public Benefit and Privacy Panel (PBPP - Scotland) - currently held data; XRB13020, Privacy Advisory Committee (PAC-Scotland; predecessor to PBPP)
Duration of Study in the UK
2 years, 5 months, 31 days
Research summary
Our research team focusses on the provision of health services for children, including health outcomes for children with chronic conditions, the impact of respiratory infections on use of secondary care services, and the health of vulnerable children and adolescents. We currently hold an extract of birth records linked to maternity, hospital, cancer registration, vaccination, public health laboratory and death records for all children born in Scotland between 1981 and June 2015. All data we hold are pseudonomised. We have used these data for research into risk factors for hospital admissions and mortality in relation to respiratory infection (including influenza and respiratory syncytial virus), and to investigate markers of adversity and distress (hospital admissions for self-harm, drug/alcohol and violent injuries). This work has been funded by the National Institute for Health Research (NIHR, through a postdoctoral fellowship to PH, the PI of this application) and the Department of Health through the Children’s Policy Research Unit (https://www.ucl.ac.uk/cpru).
We are now planning to extend these analyses to incorporate linkage to mothers’ longitudinal health records and community dispensing data. The health of mothers and children is closely linked, and government policy supports ‘whole family’ or ‘think family’ approaches. We aim to generate evidence that can help services understand associations between mother and child health care needs.
We are seeking permissions to use the linked Scottish health data for three projects to:
-investigate long-term outcomes (death, hospital admission, pregnancy) in relation to multiple adversity in adolescents (aged under 25 years) and their families.
-examine the association between risk factors at birth or during infancy and respiratory health in later childhood.
-describe variation in health outcomes community drug dispensing, emergency hospital admissions, mortality) among cohorts of children with chronic conditions and their mothers and siblings.
REC name
South East Scotland REC 02
REC reference
18/SS/0117
Date of REC Opinion
21 Sep 2018
REC opinion
Favourable Opinion