Long-term durability of trans-catheter aortic heart valves
Research type
Research Study
Full title
Echocardiographic evaluation of long-term valve function in patients who have undergone trans-catheter aortic valve implantation (TAVI)
IRAS ID
224263
Contact name
Daniel James Blackman
Contact email
Sponsor organisation
Leeds Teaching Hospitals NHS Trust
Duration of Study in the UK
5 years, 0 months, 1 days
Research summary
Trans-catheter aortic valve implantation (TAVI) is a novel keyhole aortic valve replacement procedure that has emerged as an alternative to open-heart surgery to treat patients with narrowed aortic heart valves. However, little information is available about how long TAVI heart valves last. The purpose of this study is to assess long-term valve function after TAVI. Patients who underwent TAVI at least 5 years previously (prior to end-2011) and are still alive will have their most recent assessment of heart valve function by trans-thoracic echocardiography (TTE) (an ultrasound scan of the heart) compared to the ultrasound scan that was performed immediately or soon after the TAVI procedure, to see if there is any evidence of deterioration in valve function. Patients who have been unable to attend the hospital for a routine clinical TTE scan will be approached for consent to undergo a portable bedside TTE scan at their place of residence.
REC name
Yorkshire & The Humber - South Yorkshire Research Ethics Committee
REC reference
17/YH/0337
Date of REC Opinion
5 Oct 2017
REC opinion
Favourable Opinion