LOGIC (LOw carbohydrate diets for Glucose Control in type 2 diabetes)

• Research type

  Research Study

• Full title

  Disentangling the contribution of weight loss and diet composition on glycaemia in type 2 diabetes.

• IRAS ID

  334413

• Contact name

  Sam West

• Contact email

  sam.west@phc.ox.ac.uk

• Sponsor organisation

  University of Oxford

• ISRCTN Number

  ISRCTN33756948

• Duration of Study in the UK

  1 years, 1 months, 3 days

• Research summary

  We now know that type 2 diabetes can be put into remission using dietary approaches to induce significant weight loss. A dietary strategy of interest to researchers and practitioners is the low carbohydrate diet. Growing evidence now suggests that low carbohydrate diets are safe and effective for weight loss and improving glycemia. However, it is currently unclear whether this improvement in glycemia is due to the low carbohydrate per se, or whether it can be explained by the weight loss that is associated with adopting a low carbohydrate diet.
  We aim to address this gap in the evidence and evaluate 1) the effect of a low carbohydrate diet designed to induce weight loss on glycemia and insulin sensitivity, and 2) the effect of a low carbohydrate diet designed to maintain body weight on glycemia and insulin sensitivity.
  

• REC name

  London - Central Research Ethics Committee

• REC reference

  24/LO/0070

• Date of REC Opinion

  9 Feb 2024

• REC opinion

  Favourable Opinion