Link MAP-CLD
Research type
Research Study
Full title
Management of patients with chronic liver disease admitted to hospital as an emergency: Data Linkage Study.
IRAS ID
311274
Contact name
William Bernal
Contact email
Sponsor organisation
King’s College Hospital NHS Foundation Trust
Clinicaltrials.gov Identifier
NIHR13296, NIHR Grant number
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Liver disease is a serious and increasing health problem in the UK. However, people with liver disease often do not know that they are affected until they need to be admitted to hospital as an emergency. These people are often very ill, and a quarter of them die within two months of coming into hospital. The care they get when they are in hospital, and after being discharged, varies greatly across the country. This variation in care has major effects on how long they will live. Survival of those who live in the most deprived areas is half that of those who live in the most well-off ones.
We want to understand how and why the place where people live and the care that is available to them affect the way they are treated and their survival. We also want to see how variation in outpatient care after discharge makes a difference. Through this research we hope to understand what clinical practices have the best results and how we can guarantee that they are delivered across the country.
To do this research, we will gather very detailed information about the arrangements for care given to people with liver disease in each hospital in England and then use the health information routinely recorded when people are treated in these hospitals. We will ‘link’ together information from different parts of the NHS into a single database so we can analyse the complete course of people’s illness. After removing names and all other identifying information, we will analyse data from more than 100,000 people with liver disease who had emergency admissions to NHS hospitals in England over more than a decade.
REC name
London - Harrow Research Ethics Committee
REC reference
22/LO/0614
Date of REC Opinion
23 Sep 2022
REC opinion
Favourable Opinion