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Linguistic markers of risk for future Alzheimer’s Disease

  • Research type

    Research Study

  • Full title

    Linguistic markers of risk for future Alzheimer’s Disease

  • IRAS ID

    170680

  • Contact name

    Alison Wray

  • Contact email

    WrayA@cardiff.ac.uk

  • Sponsor organisation

    Cardiff University

  • Duration of Study in the UK

    1 years, 0 months, 0 days

  • Research summary

    This project aims to find out whether there are differences in the language of people at high and low genetic risk of developing Alzheimer’s in the future, and which other biomarkers of risk (identified via brain scans, cerebral spinal fluid analysis, cognitive tests, etc.) correlate with any such language differences. The data will come from unimpaired volunteers aged 40-59, who are part of an existing research cohort study; the PREVENT Research Programme. Via an online survey format, participants will provide written answers to questions and complete linguistic tasks. The language they produce in this way will be analysed to measure, among other things, grammatical complexity, vocabulary choices and the density of ideas in the text.

  • REC name

    London - Camden & Kings Cross Research Ethics Committee

  • REC reference

    15/LO/0093

  • Date of REC Opinion

    3 Feb 2015

  • REC opinion

    Favourable Opinion