Lifestyle Intervention For Liver Transplantation
Research type
Research Study
Full title
Development and feasibility testing of a behavioural intervention targeting multiple lifestyle behaviours to improve long term outcomes following liver transplantation
IRAS ID
190850
Contact name
James Prentis
Contact email
Sponsor organisation
The Newcastle Upon Tyne NHS Foundation Trust
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
NCT02696655, Clinicaltrials.gov
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Liver transplantation is associated with the onset of numerous health conditions including diabetes, obesity, and high blood pressure. The negative impact of these conditions upon survival is particularly prevalent in our post liver transplant population. As these conditions are often associated with lifestyle factors, they have the potential to be prevented or improved. Behaviour change interventions targeting lifestyle behaviours have shown to be effective for increasing physical activity and changing diet in a range of clinical populations. However, currently there is no intervention designed for use with liver transplant patients. Furthermore, clinical teams are often not trained to target lifestyle behaviours effectively in routine practice.
Aim
To develop and feasibility test a behavioural intervention that will target a range of lifestyle behaviours (e.g., physical activity/exercise, diet, smoking) in the context of liver transplantation.Intervention
A multifaceted behavioural intervention (training for clinical teams and resources for patients) will be co-developed with patients, healthcare professionals, a designer and health psychologist with expertise in lifestyle behaviour change. Focus group discussions will be conducted to better understand skills/support requirements of healthcare professionals and patients and to inform intervention content. Once developed, the intervention will be feasibility tested in practice by patients and healthcare professionals and feedback will facilitate optimisation.Outcomes
To determine whether the intervention developed is acceptable, feasible, usable and helpful to patients and healthcare professionals. Data will also be collected on specific risk factors to inform a power calculation for future studies as well as obtaining a preliminary understanding of whether the intervention could be of benefit.Future work
If the intervention proves to be feasible and acceptable we will apply for further funding from research bodies to pilot the intervention on a larger scale.REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
16/NE/0144
Date of REC Opinion
29 Apr 2016
REC opinion
Favourable Opinion