LIESL v1

  • Research type

    Research Study

  • Full title

    LIESL - London Investigation into diElectric Scanning of Lesions

  • IRAS ID

    222459

  • Contact name

    Steven Allen

  • Contact email

    stevenallen@nhs.net

  • Sponsor organisation

    Royal Marsden NHS Foundation Trust

  • Clinicaltrials.gov Identifier

    NCT03302819

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    The MARIA breast imaging system is a novel CE-marked radio-frequency (RF) medical imaging device. The system employs an electromagnetic imaging technique that exploits the dielectric contrast between normal and cancerous tissues. MARIA is a safe, comfortable imaging system that has the potential to support the early diagnosis of breast cancer. The performance and imaging characteristics of MARIA are not yet well demonstrated. We aim to evaluate some aspects of this potentially important new technology by determining the proportion of patients with breast cancer in whom breast cancer is correctly identified by MARIA. In addition a pilot study will be performed to investigate the imaging characteristics and performance of MARIA in the assessment of benign and malignant lesions in patients attending the symptomatic breast clinic. Women with a confirmed or strongly suspected breast cancer and those attending symptomatic clinics are all eligible. The study is expected to last between 12-24 months and patients will undergo a 5-10 minute scan on the same day as any other planned diagnostic imaging such as a mammography or ultrasound.

  • REC name

    London - London Bridge Research Ethics Committee

  • REC reference

    18/LO/0232

  • Date of REC Opinion

    27 Mar 2018

  • REC opinion

    Further Information Favourable Opinion