LCNEC Foundations (LCNEC-F) V1.0
Research type
Research Database
IRAS ID
352523
Contact name
Colin Lindsay
Contact email
Research summary
LCNEC Foundations: Defining Care and Improving UK Outcomes for High Grade Pulmonary Large Cell Neuroendocrine Carcinomas (LCNEC)
REC name
East of England - Cambridge East Research Ethics Committee
REC reference
25/EE/0152
Date of REC Opinion
13 Nov 2025
REC opinion
Further Information Favourable Opinion
Data collection arrangements
Pulmonary large cell neuroendocrine carcinoma (otherwise known as LCNEC) is a rare lung cancer with limited known data to guide treatment decisions and improve patient outcomes. These cancers are very aggressive and currently patient outcomes are poor. The research database aims to gather and analyse data on this condition. This database will help clinicians and researchers help understand how treatments for patient works, identify patterns in patient outcomes with the aim to improve patient care in the future.
This research database will collect patient identifiable data such as NHS number (for tracking purposes only) and date of birth , information on diagnosis and treatment, and information on outcomes. The data will be collected directly from patient records at NHS sites.Research programme
This database is part of a larger research programme focused on pulmonary large cell neuroendocrine carcinoma (LCNEC), a rare form of lung cancer. The programme brings together several organisations working closely to improve care and outcomes for people affected by this disease. Together, they aim to build and maintain a world-class research system and information resource to support learning and discovery. The partners involved are The Christie NHS Foundation Trust, the British Thoracic Oncology Group (which brings together healthcare professionals involved in lung cancer across the UK), and Boehringer Ingelheim. The database supports a research community made up of scientists, healthcare professionals, and patient representatives. Their shared goal is to ensure the research carried out is meaningful, relevant, and beneficial to both patients and the wider public.
Research database title
LCNEC Foundations: Defining Care and Improving UK Outcomes for High Grade Pulmonary Large Cell Neuroendocrine Carcinomas (LCNEC)
Establishment organisation
The Christie NHS Foundation Trust
Establishment organisation address
Wilmslow Road
Withington
Manchester
M20 4BX