Laparoscopic Para-oesophageal Hiatal Hernia Repair
Research type
Research Study
Full title
Laparoscopic Para-oesophageal Hiatal Hernia Repair: A Single Centre Cohort Study Investigating the Effect on Cardiorespiratory Function and Quality of Life
IRAS ID
276327
Contact name
Richard J McGregor
Contact email
Sponsor organisation
University of Edinburgh
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
Hiatal surgery is usually undertaken to manage gastrointestinal symptoms, such as reduced appetite, vomiting after eating, regurgitation and upper abdominal pain. Increasingly, patients are referred from colleagues in Respiratory medicine and Cardiology for consideration of surgery to improve cardio-respiratory symptoms such as breathlessness, which can limit day to day activities. Currently there is limited evidence regarding the effect of hiatal surgery on cardio-respiratory outcomes.
Our research question is to ask whether hiatal hernia surgery will improve cardio-respiratory function, and in turn lead to measurable improvements in functional performance and quality of life measures (in addition to established improvements in gastrointestinal symptoms).
All patients undergoing elective para-oesophageal hiatial hernia repair at the Edinburgh Royal Infirmary will be eligible for this prospective, single centre, cohort study. We envisage the study will run for 3 years in order to collect sufficient data for statistically analysis. There will be no change to the standard of care i.e. laparoscopic (key hole) repair. The study will have the dual function of measuring patient centered outcomes, alongside objective assessments of cardio-respiratory function.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
20/WM/0074
Date of REC Opinion
31 Mar 2020
REC opinion
Further Information Favourable Opinion