Lab-on-a-chip detection of cervical cancer tumour markers
Research type
Research Study
Full title
MOlecular Diagnostics Using a novel LAb-on-a-chip and MRI for detecting cervical cancer (MODULAR)
IRAS ID
238475
Contact name
Nandita deSouza
Contact email
Sponsor organisation
Institute of Cancer Research
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 5 months, 0 days
Research summary
This study aims to establish whether tumour markers measured from cytological samples can improve cervical cancer detection both prior to treatment and after treatment during follow up.
All patients with presumed early cervical cancer referred to the Gynaecological Oncology Unit at The Royal Marsden Hospital and patients previously surgically treated for early cervical cancer with a suspected recurrence will be invited to participate.
Women attending the Colposcopy Unit at St George's Hospital, with a normal cervix will be invited to participate.
An endovaginal receiver coil has been designed and developed at the
Institute of Cancer Research and Royal Marsden NHS Foundation Trust for use at high field strengths (3T).
A cytology swab, similar to a smear test, will be used to collect a sample of cells to evaluate the presence of tumour markers.
The presence of tumour markers will be measured by a lab-on-a-chip and polymerase chain reaction (PCR) testing system.REC name
London - Surrey Research Ethics Committee
REC reference
18/LO/0865
Date of REC Opinion
24 Jul 2018
REC opinion
Further Information Favourable Opinion