KTOP

• Research type

  Research Study

• Full title

  Kidney Transplantation in Older People (KTOP): Understanding the Patient's Experience

• IRAS ID

  273153

• Contact name

  Edwina A Brown

• Contact email

  e.a.brown@imperial.ac.uk

• Sponsor organisation

  Imperial College London

• Duration of Study in the UK

  1 years, 11 months, 1 days

• Research summary

  Transplantation for older patients remains a challenge. With increasing numbers of older patients developing end-stage kidney disease (ESKD), there is an expectation from many that transplantation should be offered. Frailty and
  cognitive impairment are common in this patient group but often under-recognised. Little is known about the impact of frailty and its components, particularly cognitive impairment, on transplant outcomes, patient experiences, quality of life, and adherence to complex immunosuppression drug regimes.

  This study aims to understand the lived experience of older people with frailty, from being on the kidney transplant wait list, to receiving a transplant and adjusting to life with a transplanted kidney. We hope to explore the older patient's expectations, perspectives, and experiences of having advanced kidney disease and how this may change as they progress through the stages of transplantation. We hope to describe how older people experience life and health after kidney transplantation, including the changes or lack of changes compared to life on dialysis.

  A combination of methods will be used to study the patient’s perspectives including semi-structured interviews (remotely), and the option for patients to keep a diary, or take photographs to capture in the moment experiences and include patients who may not be able to complete a diary themselves. This multi-method approach will allow us to include a wide variety of patients and also fully explore the changing perspectives and experiences of patients. The study will include both patients who remain on the wait list and those that undergo transplantation.

  Overall this information will prove invaluable to understanding how older people with frailty cope with the process of transplantation and will be critical to supporting and improving services for older people in the future.

• REC name

  London - Stanmore Research Ethics Committee

• REC reference

  20/LO/1208

• Date of REC Opinion

  15 Dec 2020

• REC opinion

  Further Information Favourable Opinion